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HIV & AIDS Health Center

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First at-Home HIV Test Nears Approval

OraQuick Mouth-Swab Test: Results in 20 Minutes; False Assurance an Issue


Panel member Susan Buchbinder, MD, director of HIV research at San Francisco's health department and a long-time AIDS researcher, noted that while some people may get inaccurate results, the test likely will alter people's HIV risk behavior.

"A positive HIV test does reduce risk behavior. A negative test doesn't have much of an influence," Buchbinder said. "We must assume there will be some incorrect results. The question is how do we help people understand a negative result might not truly mean a person is negative for HIV."

There's another catch to the OraQuick in-home test: the "window period." The test detects anti-HIV antibodies, but these antibodies appear many weeks after infection.

A recent study suggests that rapid HIV tests such as OraQuick will be accurate two months after infection. OraSure says that to be safe, people should assume the OraQuick test will miss any new HIV infection contracted in the past three months.

This means that people with any HIV risk behavior -- such as unprotected sex or needle sharing -- will need regular retesting, as is true with any HIV test. And confirmatory testing at a doctor's office or free clinic is strongly advised for those who test positive but also for those who test negative despite high-risk behavior.

Is America Ready for Home HIV Testing?

HIV testing has been controversial ever since it began in 1985. In those days, before HIV drugs were developed for treatment, a positive test result was considered a death sentence.

Stigma was enormous. Children with HIV were kicked out of school. Adults with HIV lost their jobs. It took great courage for a person with HIV to tell anyone about it.

And because a positive test had such a dramatic impact, HIV testing was done only along with counseling, both before and after the result was known.

While these safeguards were necessary, they threw up barriers to testing. The hassle is one reason why so many people at risk of HIV infection never get tested -- or don't get regular HIV tests.

In 1989 and again in 1990, the FDA was approached by companies that wanted to sell HIV tests over the counter. But according to an FDA briefing document, "the state of technology and public-health thinking at that time was not conducive to such a claim."

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