Skip to content

HIV & AIDS Health Center

Font Size

HIV: Nonprogressors and HIV-Resistant People - Topic Overview

A few people with HIV are described as nonprogressors. These people have HIV that does not progress to more severe symptoms or disease, but they can still spread HIV. Most nonprogressors:

  • Have lived with the infection for 10 to 15 years and remained healthy.
  • Do not have declining CD4+ cell counts.
  • Have a very low level of HIV in their blood.

A small number of people never become infected with HIV despite years of exposure to the virus. For example, they may have repeated, unprotected sex with an infected person. These people are said to be HIV-resistant. These people are never infected, so they can't spread HIV.

Recommended Related to HIV/AIDS

HIV, AIDS, and Cytomegalovirus

Cytomegalovirus (CMV) is a herpes virus. It is very common, infecting up to 80% of people in the U.S. by age 40. Normally, it hides out in the body. This is not a problem for most people because a healthy immune system can easily control it. However, it can cause severe disease in people with HIV (human immunodeficiency virus). It's able to take advantage of a weakened immune system, which is why it's called an opportunistic infection. The most common illness CMV causes is retinitis, an eye infection...

Read the HIV, AIDS, and Cytomegalovirus article > >

Studies are under way to determine why some people either don't become infected with HIV or, if they do, why they don't develop symptoms or lose CD4+ cells. Research has shown that:

  • Some people's CD4+ cells are relatively resistant to HIV. If HIV cannot attach itself to CD4+ cells, it cannot destroy them.
  • Some people's immune systems may be better able to destroy the virus.
  • Some strains of HIV may not be as harmful.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: April 05, 2012
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    1
    Next Article:

    HIV: Nonprogressors and HIV-Resistant People Topics

    Today on WebMD

    misconception
    How much do you know?
    contemplative man
    What to do now.
     
    research
    Should you be tested?
    HIV under microscope
    What does it mean?
     
    HIV AIDS Screening
    Slideshow
    man opening condom wrapper
    Quiz
     
    HIV AIDS Treatment
    Feature
    Discrimination Stigma
    Feature
     
    Treatment Side Effects
    Feature
    grilled chicken and vegetables
    Article
     
    obese man standing on scale
    Article
    cold sore
    Article
     

    WebMD Special Sections