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Gangrene

Gangrene is the death and decay of tissue that usually occurs when the blood supply to the tissue is cut off by injury or infection. After the tissue is dead, bacteria may infect the tissue and cause decay.

Gangrene may affect small areas, such as fingers or toes that have been frostbitten, or larger areas of tissue, such as part of the foot. People who have impaired blood flow, such as people with diabetes, may be at higher risk of gangrene if they have skin wounds and infections that are not treated promptly.

Gangrene is treated by restoring blood flow to the affected area, treating any infection, and removing the dead and dying tissue. If it is severe, gangrene sometimes requires that a part of the body, such as a finger, toe, or foot, be amputated.

Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Last Updated May 25, 2007

WebMD Medical Reference from Healthwise

Last Updated: May 25, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.