In some people, using medicine to stop heartburn causes the stomach to produce even more acid, making heartburn worse. This is called acid rebound.
If you take acid reducer medicine (such as an H2 blocker or a proton pump inhibitor) every day to prevent heartburn, do not stop taking the medicine suddenly. By taking less and less medicine over time (called tapering), you may be able to prevent acid rebound.
WebMD Medical Reference from Healthwise