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Blood type

Human blood is typed according to whether certain markers, called antigens, are present on the surface of red blood cells. The ABO system classifies blood as type A, B, AB, or O based on the presence or absence of the A and B antigens; the Rh system classifies blood as negative or positive based on the presence or absence of the Rh antigen (Rh factor).

If red blood cells have:

  • The A antigen, they are type A blood.
  • The B antigen, they are type B blood.
  • Both the A and B antigens, they are type AB blood.
  • Neither A nor B antigens, they are type O blood.

Rh blood typing determines the presence (+) or absence (–) of the Rh factor. If red blood cells:

  • Have the Rh antigen, they are Rh-positive.
  • Do not have the Rh antigen, they are Rh-negative.
Author Caroline Rea, RN, BS, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Michele Cronen
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Anne C. Poinier, MD
- Internal Medicine
Specialist Medical Reviewer Joseph O'Donnell, MD
- Hematology/Oncology
Last Updated December 27, 2007

WebMD Medical Reference from Healthwise

Last Updated: December 27, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.