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Carrier

A carrier is a person who can pass an inherited (genetic) disease on to his or her children but may not have the disease. The person can also pass on carrier status.

Some diseases are caused by defects in a person's genes or chromosomes. Each person inherits 23 chromosomes from each parent and so has 23 pairs of chromosomes. One or both of the chromosomes in a pair may be damaged or defective in a way that causes an inherited (genetic) disease.

In some cases both chromosomes in a pair must be defective for the person to have the disease. This is known as an autosomal recessive disease. Some genetic disorders are caused by defects in the X and Y chromosomes that determine a person's sex. If only one of the chromosomes in the pair is affected, the person may be a carrier.

Author Maria G. Essig, MS, ELS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman
Primary Medical Reviewer Anne C. Poinier, MD
- Internal Medicine
Specialist Medical Reviewer Siobhan M. Dolan, MD, MPH
- Reproductive Genetics
Last Updated November 20, 2007

WebMD Medical Reference from Healthwise

Last Updated: November 20, 2007
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