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Effects of exposure to diethylstilbestrol (DES)

Between 1948 and 1971, millions of women took a drug called diethylstilbestrol (DES) to prevent miscarriage.

Daughters born to women who took DES while pregnant have a slightly higher risk of developing:

  • Abnormal cervical cells that cause an abnormal Pap test result.
  • Cancer of the vagina.
  • Structural problems in the reproductive organs (such as a T-shaped uterus), which can cause infertility.
Author Shannon Erstad, MBA/MPH
Editor Kathleen M. Ariss, MS
Associate Editor Denele Ivins
Associate Editor Pat Truman
Primary Medical Reviewer Joy Melnikow, MD, MPH
- Family Medicine
Specialist Medical Reviewer Barbara S. Apgar, MD, MS
- Family Medicine, Women's Health
Specialist Medical Reviewer Ross Berkowitz, MD
- Obstetrics and Gynecology
Last Updated January 12, 2007

WebMD Medical Reference from Healthwise

Last Updated: January 12, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.