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Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is a rare nerve disorder that occurs when the body's own defenses (immune system) attack part of the peripheral nervous system.

Symptoms usually start with numbness or tingling in the fingers and toes, followed by muscle weakness in the legs, arms, and other muscles that develops over a period of days to weeks and can progress to complete paralysis. Difficulties in breathing and swallowing can also develop. The cause of this disease is not known, but it often occurs after a viral or bacterial infection.

Guillain-Barré is treated with immunotherapy, which boosts the body's immune system and its ability to fight disease. Although GBS can be life-threatening, most people recover with few lasting problems.

By Healthwise Staff
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Colin Chalk, MD, CM, FRCPC - Neurology
Last Revised July 22, 2010

WebMD Medical Reference from Healthwise

Last Updated: July 22, 2010
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