Idiopathic thrombocytopenic purpura (ITP)

Idiopathic thrombocytopenic purpura (ITP)

Idiopathic thrombocytopenic purpura (ITP) is an immune disorder in which the body attacks the cells responsible for blood clotting (platelets), resulting in mild to severe bleeding. The cause of ITP is not known (idiopathic).

People with this disorder may have bruises or black-and-blue marks (purpura) on the skin. Internal bleeding is a more serious complication that can occur.

Some cases of ITP may go away on their own and do not require treatment. In other cases, treatment may be needed to control bleeding. Steroid medication (such as prednisone) also may be needed to suppress the immune system. An intravenous (IV) infusion of a substance made from human blood plasma (immune globulin) may be given. On rare occasions, the spleen may need to be removed.

Credits

Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Last Updated May 25, 2007