WebMD
Font Size
A
A
A

Macroglobulinemia

Macroglobulinemia (Waldenstrom's macroglobulinemia) is a rare type of cancer that causes overproduction of a type of the antibody (immunoglobulin) IgM. The disease causes the blood to thicken and reduces the body's ability to fight off infection.

Symptoms may not be present in mild cases. In more severe cases, symptoms of macroglobulinemia include weakness and fatigue, recurring infections, problems with thinking and making decisions, shortness of breath, swollen glands, and nerve problems. Treatment may include chemotherapy and a process that removes the antibodies from the blood (plasmapheresis).

Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Last Updated May 25, 2007

WebMD Medical Reference from Healthwise

Last Updated: May 25, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.