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Macrovascular diabetes diseases

Macrovascular complications of diabetes are those that affect the large blood vessels. Diabetes damages the lining of blood vessels, causing them to narrow, which decreases the blood supply and eventually causes injury to the affected area.

  • When blood vessels that supply the brain and heart are affected, a heart attack or stroke may occur.
  • When the large blood vessels in the legs are affected, problems with blood circulation to the legs and feet may develop, causing changes in skin color, decreased sensation, and leg cramps (peripheral arterial disease).

Keeping blood sugar levels tightly within a safe range helps prevent macrovascular disease.

Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Last Updated May 25, 2007

WebMD Medical Reference from Healthwise

Last Updated: May 25, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.