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Medications that may cause a rash

Many medications can cause a rash. Some of the more common medications that cause rashes are:

  • Angiotensin-converting enzyme (ACE) inhibitors for high blood pressure, such as captopril, enalapril, fosinopril, or lisinopril.
  • Antibiotics, such as penicillin, cephalosporins, sulfonamides, furadantin, or vancomycin.
  • Anticonvulsants, such as carbamazepine or valproate.
  • Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen.
  • Barbiturates, such as amobarbital or pentobarbital.
  • Blood and blood products.
  • Complementary and alternative medications, such as echinacea.
  • Contrast dyes used in X-ray studies.
  • Enzymes, such as trypsin and streptokinase.
  • Pain medications that contain codeine and codeine-like compounds.
  • Phenylbutazone, such as Azolid, Butatab, Butazolidin, Butazone-100, or Phenylbutazone Alka.
  • Sulfonamide derivatives, such as hydrochlorothiazide.

If a rash occurs after you have begun a new medication:

  • Call the health professional who prescribed the medication to determine whether you should stop taking the medication or take a different one. An appointment may not be necessary. Do not take another dose of the medication until you have spoken to your health professional.
  • If you are taking a nonprescription medication, stop taking it. Call your health professional if you feel you need to continue taking the medication.
Author Jan Nissl, RN, BS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Primary Medical Reviewer William M. Green, MD
- Emergency Medicine
Specialist Medical Reviewer Alexander H. Murray, MD, FRCPC
- Dermatology
Last Updated August 29, 2006

WebMD Medical Reference from Healthwise

Last Updated: August 29, 2006
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.