Medications that may cause chest pain

Medications usually do not cause chest pain. However, some medications, such as aspirin, ibuprofen, and some antibiotics may cause stomach acid to back up (reflux) into the esophagus, causing pain or discomfort behind the breastbone, in the center of the chest (heartburn).

The use of illegal drugs, especially cocaine and amphetamines, may cause a rapid heart rate and chest pain.

If a chest pain occurs after you have begun a new medication:

• Call the health professional who prescribed the medication to determine whether you should stop taking the medication or take a different one. An appointment may not be necessary. Do not take another dose of the medication until you have spoken to your health professional.
• If you are taking a nonprescription medication, stop taking it. Call your health professional if you feel you need to continue taking the medication.