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Medicines that may cause lightheadedness or vertigo

Many prescription and nonprescription medicines can cause lightheadedness or vertigo. The degree of lightheadedness or vertigo caused by a specific medicine will vary.

Some medicines are more likely to cause lightheadedness, such as:

  • Antianxiety medicines, such as Librium, Valium, or Xanax.
  • Antihistamines, such as Benadryl or Chlor-Trimeton.
  • Diuretics, such as hydrochlorothiazide, Diuril, Dyazide, Lasix, or spironolactone.
  • Blood pressure medicines (antihypertensives), such as Aldomet, Inderal, Lopressor, verapamil, Catapres, or reserpine.
  • Medicines used to treat seizure disorders, such as Dilantin or Tegretol.
  • Pain medicines, such as hydrocodone, morphine, Darvon, or codeine.
  • Selective serotonin inhibitors (SSRIs), such as Prozac and Zoloft.
  • Serotonin receptor agonists (triptans), such as sumatriptan succinate (Imitrex), almotriptan malate (Axert), or rizatriptan (Maxalt).
  • Steroids, such as prednisone, methylprednisolone, or dexamethasone.
  • Tricyclic antidepressants, such as Elavil, Pamelor, or Tofranil.
  • Anti-psychotic medicines, such as chlorpromazine, fluphenazine, haldol, or thioridazine.

Some medicines can cause damage to the inner ear (ototoxic), which can affect balance and hearing and cause vertigo. The most commonly prescribed medicines that can damage the inner ear are antibiotics, such as:

  • Streptomycin, which primarily affects balance.
  • Neomycin and kanamycin, which can cause hearing loss.
  • Gentamicin and tobramycin, which can affect balance and hearing but are more likely to affect balance.

If you think a prescription or nonprescription medicine may be causing your lightheadedness or vertigo, call your doctor.

Author Jan Nissl, RN, BS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Denele Ivins
Associate Editor Tracy Landauer
Primary Medical Reviewer William M. Green, MD
- Emergency Medicine
Specialist Medical Reviewer Colin Chalk, MD, CM, FRCPC
- Neurology
Last Updated February 27, 2007

WebMD Medical Reference from Healthwise

Last Updated: February 27, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.