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Oral diabetes medications that can cause low blood sugar

The following sulfonylurea medications for diabetes can cause low blood sugar as a side effect.

  • Glipizide (Glucotrol)
  • Glyburide (such as DiaBeta, Glynase, Micronase)
  • Glimepiride (Amaryl)

Repaglinide (Prandin) and nateglinide (Starlix) are not sulfonylurea medications. However, they work in the same way and can also cause low blood sugar as a side effect.

You are unlikely to develop low blood sugar levels if you are taking:

  • Metformin (Glucophage).
  • Rosiglitazone (Avandia).
  • Pioglitazone (Actos).
Author Caroline Rea, RN, BS, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Caroline S. Rhoads, MD - Internal Medicine
Specialist Medical Reviewer Matthew I. Kim, MD - Endocrinology & Metabolism
Last Updated June 16, 2008

WebMD Medical Reference from Healthwise

Last Updated: June 16, 2008
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