After your infant is discharged from the neonatal intensive care unit (NICU), you may need to take special precautions for car travel.
Some premature infants cannot sit in a car seat without slouching over, which interferes with their breathing and oxygen supply. Before discharging your infant from the hospital, the NICU staff will monitor for breathing and oxygen problems while your infant sits in your car seat. If he or she "fails" the car seat test, a car bed will be necessary for transport until your infant is stronger. Many hospitals have car beds available to rent or lend.
If your infant is sent home with oxygen, a monitor, or other supportive technology, secure the equipment under a vehicle seat or on the floor during travel.
WebMD Medical Reference from Healthwise