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South African tick-bite fever

South African tick-bite fever is a disease passed to humans by ticks that are infected with an organism called Rickettsia africae.These ticks, known as buffalo ticks, usually live on cattle in southern Africa.

Symptoms usually begin within 8 days after the tick bite and may last for 1 to 15 days. Symptoms may include:

  • Fever and chills.
  • Multiple ulcerlike or crusty skin sores.
  • Swelling in the area of the skin sores.
  • Generalized swollen glands.

Unlike some tick-borne diseases, South African tick-bite fever does not cause a rash.

A person who has South African tick-bite fever is treated with antibiotics (usually doxycycline).

Author Jeannette Curtis
Author Caroline Rea, RN, BS, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Tracy Landauer
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Last Updated May 25, 2007

WebMD Medical Reference from Healthwise

Last Updated: May 25, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.