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Thrombocytopenia

Thrombocytopenia is a disorder in which there are too few platelets and the blood does not clot properly. People who have thrombocytopenia may bleed a lot from an injury because they have an abnormally low number of platelets.

Some conditions or diseases lead to thrombocytopenia because they destroy a person's platelets or interfere with their production. Certain medicines may also cause thrombocytopenia. A person who has a low platelet count with no known cause is said to have idiopathic thrombocytopenic purpura (ITP).

Symptoms of thrombocytopenia include:

  • Easy or excessive bruising.
  • Pinpoint-sized red spots (petechiae) around the feet and ankles. In more serious cases of thrombocytopenia, the spots are larger and more widespread (purpura).
  • Nosebleeds.
  • Heavy menstrual flow.

Treatment for low platelets starts with finding a cause that can be eliminated, such as changing a drug the person is taking or treating an infection. Treatment may include platelet injections into a vein, called platelet transfusion; taking medicines to stop destruction of the platelets; taking medicine that helps the body make more platelets; or surgery to remove the spleen.

Author Caroline Rea, RN, BS, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Michele Cronen
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Joseph O'Donnell, MD - Hematology/Oncology
Last Updated December 27, 2007

WebMD Medical Reference from Healthwise

Last Updated: December 27, 2007
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.