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Toxic reaction to insect or spider venom

A toxic reaction occurs when insect or spider venom acts like a poison in the body. This type of reaction can occur from one bite or sting from a highly toxic insect or spider, or from multiple bites or stings from insects or spiders not normally considered poisonous.

Symptoms of a toxic reaction vary depending on the insect or spider, the toxicity of the venom, and the amount of venom injected. Most often symptoms lessen or go away within 48 hours. Although hives and difficulty breathing may occur in an allergic reaction, these symptoms will not occur in a toxic reaction. It is possible to have both a toxic reaction and an allergic reaction at the same time.

Signs and symptoms of a toxic reaction may include:

  • Nausea or vomiting.
  • Diarrhea.
  • Fever.
  • Weakness.
  • Lightheadedness.
  • Rapid swelling at the site of the sting.
  • Muscle spasms.
  • Headache.
  • Drowsiness.
  • Fainting (syncope).
  • Uncontrollable jerking movements (seizures).

A toxic reaction may lead to heart rhythm problems, shock, and death.

Author Caroline Rea, RN, BS, MS
Editor Maria G. Essig, MS, ELS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman
Primary Medical Reviewer William M. Green, MD
- Emergency Medicine
Specialist Medical Reviewer Harold S. Nelson, MD
- Allergy and Immunology
Last Updated January 22, 2008

WebMD Medical Reference from Healthwise

Last Updated: January 22, 2008
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.