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Von Willebrand's disease

Von Willebrand's disease is an inherited bleeding disorder that prevents blood from clotting properly. In this disease, a protein in the body's blood system (von Willebrand factor) is missing or does not work well, and the blood cells (platelets) cannot stick together normally to form clots at the site of bleeding.

Symptoms of von Willebrand's disease may include excessive bleeding after injury, frequent nosebleeds, heavy menstrual flow, easy bruising, blood in the urine or stool, and bleeding from the gums. Equal numbers of men and women have this disease.

Von Willebrand's disease can be treated with home treatment, like not taking aspirin, and with medicine that increases the amount of von Willebrand clotting factor in the blood. Treatment also focuses on preventing and stopping bleeding.

Author Robin Parks, MS
Editor Kathleen M. Ariss, MS
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Denele Ivins
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Joseph O'Donnell, MD - Hematology/Oncology
Last Updated November 24, 2008

WebMD Medical Reference from Healthwise

Last Updated: November 24, 2008
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