"Our findings do not support [the idea] that potential cardiovascular benefits of red wine consumption result from blood pressure lowering by polyphenols," says researcher Ilse Botden, MD, a PhD student at Erasmus Medical Center in Rotterdam, Netherlands.
The findings don't suggest red wine isn't still heart-healthy -- just that it doesn't seem to work by lowering blood pressure, Botden says.
The benefit of red wine and heart health, she says, ''apparently occurs in a blood pressure-independent manner."
Botden is due to present the findings today at the American Heart Association's High Blood Pressure Research 2011 Scientific Sessions in Orlando.
Botden asked 61 men and women, average age 61, to drink three types of dairy beverages. One drink contained placebo. The other two contained either 280 milligrams or 560 milligrams of red wine polyphenols. That is equal to about what is found in two or fourglasses of red wine.
They were randomly assigned to drink one of the three choices every day for four weeks.
The researchers measured blood pressures after each four-week study period. Blood pressures were taken in the office and using 24-hour measurements while the people went through their day wearing a monitor.
At the start, the men and women had borderline high blood pressure or early high blood pressure. Their readings in the office, on average, were 145/86. Ideally, blood pressure should be below 120/80.
However, in the new study, neither dose of the polyphenols lowered blood pressure.
Is it possible that something else in the wine may be needed to interact with the polyphenols, that they can't act alone?