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    Colitis, Collagenous

    Important
    It is possible that the main title of the report Colitis, Collagenous is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    Disorder Subdivisions

    • None

    General Discussion

    Collagenous colitis is a rare digestive disorder that primarily affects females and typically becomes apparent during middle age. The disorder is characterized by inflammatory changes of the mucous membranes (mucosa) of the colon (colitis) and abnormal accumulation (excessive deposition) of the protein collagen beneath the surface (epithelial) layer of the mucosa (thickened subepithelial collagenous bands). The colon is the major portion of the large intestine. The medical literature often refers to collagenous colitis as a form of "microscopic colitis," since evidence of inflammation and other abnormalities may only be confirmed through microscopic (i.e., histologic) examination of multiple tissue samples.

    Individuals with collagenous colitis typically experience episodes of chronic, watery, nonbloody diarrhea. In some instances, episodes may often occur at night (nocturnal diarrhea). Diarrheal episodes may be persistent or may occur at intervals (intermittent) over a period of weeks, months, or years. Other symptoms and findings that may occasionally be associated with such episodes include vague abdominal pain, abdominal swelling (distension), nausea, vomiting, and/or weight loss.

    The exact cause of collagenous colitis is unknown. Possible immunological, environmental, genetic, and/or other factors are under investigation as potential causes of the disorder.

    Resources

    Crohn's and Colitis Foundation of America
    386 Park Avenue South
    17th Floor
    New York, NY 10016-7374
    USA
    Tel: (212)685-3440
    Fax: (212)779-4098
    Tel: (800)932-2423
    Email: info@ccfa.org
    Internet: http://www.ccfa.org

    Digestive Disease National Coalition
    507 Capitol Court, NE
    Suite 200
    Washington, DC 20002
    Tel: (202)544-7497
    Fax: (202)546-7105
    Email: ddnc@hmcw.org
    Internet: http://www.ddnc.org

    NIH/National Institute of Diabetes, Digestive & Kidney Diseases
    Office of Communications & Public Liaison
    Bldg 31, Rm 9A06
    31 Center Drive, MSC 2560
    Bethesda, MD 20892-2560
    Tel: (301)496-3583
    Email: NDDIC@info.niddk.nih.gov
    Internet: http://www2.niddk.nih.gov/

    International Foundation for Functional Gastrointestinal Disorders
    700 W. Virginia St., 201
    Milwaukee, WI 53217
    USA
    Tel: (414)964-1799
    Fax: (414)964-7176
    Tel: (888)964-2001
    Email: iffgd@iffgd.org
    Internet: http://www.iffgd.org

    Gastro-Intestinal Research Foundation
    70 East Lake Street
    Suite 1015
    Chicago, IL 60601
    Tel: (312)332-1350
    Fax: (312)332-4757
    Email: info@girf.org
    Internet: http://www.girf.org

    Reach Out for Youth with Ileitis and Colitis, Inc.
    PO Box 857
    Bellmore, NY 11710
    USA
    Tel: (631)293-3102
    Email: info@reachoutforyouth.org
    Internet: http://www.reachoutforyouth.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    CORE
    3 St. Andrews Place
    London, NW1 4LB
    United Kingdom
    Tel: 02074860341
    Fax: 02072242012
    Email: info@corecharity.org.uk
    Internet: http://www.corecharity.org.uk

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 5/21/2008
    Copyright 1989, 1991, 1998, 2001, 2002 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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