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Ulcerative Colitis Health Center

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Ulcerative Colitis: Symptoms and Treatment

If your stomach pain is due to ulcerative colitis, there's plenty of help available.

What Causes Ulcerative Colitis?

No one knows exactly what causes ulcerative colitis, but a genetic link appears to play a part. Ashkenazi Jews are slightly more likely to get it, and, while statistics vary, about 10% to 30% of people with the disease have at least one close family member with it. Research also suggests it may be an autoimmune disease, in which the body attacks its own healthy organs and tissues. Contrary to popular belief, neither stress nor specific foods cause ulcerative colitis, although both can antagonize symptoms.

How Is Ulcerative Colitis Treated?

Medication, the core treatment, eases symptoms and sends the disease into remission without flare-ups. Mild to moderate ulcerative colitis often responds to drugs, such as aminosalicylates that reduce the inflammation of the colon. Doctors sometimes prescribe short courses of corticosteroid therapy, such as prednisone or hydrocortisone, when aminosalicylates fail to control the inflammation. In severe cases, medications that suppress the body's immune system, which in turn reduces inflammation, are used.

Because ulcerative colitis is a chronic disease, taking medication on a regular basis is key. "A lot of people like to think that once they get into remission, they don't need to take medication. [But] the medication isn't only to control symptoms; it's also to prevent them," Rubin says.

Does Ulcerative Colitis Cause Cancer?

Most people diagnosed with ulcerative colitis are concerned they will develop colon cancer, but this is rare. The lifetime incidence of colon cancer is 2.5% at 10 years, 7.6% at 30 years, and 10.8% at 50 years. Those at higher risk for cancer have a positive family history of colon cancer, long durations of colitis, extensive colon involvement, and primary sclerosing cholangitis, a complication of ulcerative colitis.

The American Cancer Society calls for screening with a colonoscopy eight years after an ulcerative colitis diagnosis if the whole colon is involved, and 12 to 15 years if only part of the colon is affected. Follow-up screening should occur every one to two years thereafter.

Does Surgery Help Ulcerative Colitis?

A small percentage of people may eventually require surgical removal of their colon. (An opening is made in the abdominal wall, and the end of the small intestine is attached to the skin of the abdomen to form an opening; stool collects in a bag attached over the opening.) This is done only if symptoms are severe and don't respond to treatment, or if complications or precancerous changes occur. Surgery is also, in essence, a cure and removes the need for medication.

Ehrlich still keeps track of bathroom locations but laughs at herself for doing it. "Now that I'm on a regular medication program, I don't have any symptoms. This has changed my world."

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Reviewed on July 19, 2011

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