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Irritable Bowel Syndrome (IBS) Health Center

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Fibromyalgia and IBS: What’s the Connection?

By Katherine Tweed
WebMD Feature
Reviewed by Jennifer Robinson, MD

Knots grip your arms and legs, and your muscles ache. Your belly has cramps, too. Could the pain be connected? If you have irritable bowel syndrome (IBS) or fibromyalgia, it’s likely you have the other one, too. They often happen together, but how they are related is not understood.

Functional Disorders

Only a small amount of people in the U.S. have fibromyalgia. But for people with IBS it’s much more common. Over half of IBS patients also have symptoms of fibromyalgia.

“In general, it is likely that they coexist for years, but they can flare at the same time or at different times,” says Lin Chang, MD, co-director of the Oppenheimer Center for Neurobiology of Stress.

IBS and fibromyalgia fall into a broad category called functional disorders. This is when your body isn’t working as it should, but doctors can’t see anything wrong with you.

The pain of IBS is centered inside your body, in the internal organs. With fibromyalgia you have another kind of pain, which is in the skin and deep tissue. Even though the source of discomfort stems from different places, researchers and doctors believe their causes are related.

In the journal Mayo Clinic Proceedings, Daniel Clauw MD, director of the Chronic Pain and Fatigue Research Center at the University of Michigan, writes that many pain experts believe that they are a single lifelong disorder that causes pain in different places over time.

How Are They Related?

With both conditions, you have more brain activity in the parts that process pain. Your sense of pain can be enhanced.

The exact problem is not well understood, but in these functional disorders, your nervous system is overly sensitive or hyperactive. Your immune systems is thought to play a role, and doctors are looking at genetics, too.

Stress can lead to any of these functional disorders. In one survey, more than half of fibromyalgia patients reported symptoms of posttraumatic stress disorder, a condition that affects the brain.

What Can You Do?

Antidepressants can help both IBS and fibromyalgia. You could also have trouble with sleeping, headaches, anxiety, and depression, so talk to your doctor about prescription medicines that could help.

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