Skip to content

    Infertility & Reproduction Health Center

    Font Size

    Egg May Lure Sperm By "Smell"

    Finding Could Lead to New Fertility Treatments, Birth Control Methods
    WebMD Health News

    March 27, 2003 -- When everything's right, sperm cells may be able to "smell" an egg, causing them to make a beeline for the target. It's a new discovery, one that could lead to advances in contraception and fertility treatments.

    A new study, appearing in the latest issue of the journal Science, explores the concept of "chemo-attraction."

    A group of German and U.S. researchers report that the activation of an "odorant receptor" -- found on the surface of sperm cells -- seems to trigger a series of events that leads the sperm to not only move towards a sperm-attracting substance called "bourgeonal," but also to move there more quickly.

    Ideally, the object of the sperm's destination would be the egg, but the scientists do not yet know if the egg itself produces some sperm-attracting compound similar to bourgeonal -- or if some other part of the female reproductive tract makes the chemical that may bind to the sperm's receptor.

    Researchers have also identified a potential problem to fertilization -- a compound called "undecanal" -- that appears to block the effect of bourgeonal. It seems to inhibit the sperm's natural attraction to this compound.

    The finding could lead to new forms of contraception, or to new fertility treatments, by manipulating the signals sent between sperm and egg, writes lead author Marc Spehr, of Ruhr University Bochum in Germany.

    Today on WebMD

    Four pregnant women standing in a row
    How much do you know about conception?
    Couple with surrogate mother
    Which one is right for you?
    couple lying in grass holding hands
    Why Dad's health matters.
    couple viewing positive pregnancy test
    6 ways to improve your chances.
    Which Treatment Is Right For You
    Conception Myths
    eddleman prepare your body pregnancy
    Charting Your Fertility Cycle
    Fertility Specialist
    Understanding Fertility Symptoms
    invitro fertilization

    WebMD Special Sections