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    Worry Lowers IVF Success

    Financial Concerns Have Big Impact on Infertility Treatment
    WebMD Health News

    April 23, 2004 -- Even though she knew it was her only chance of having a baby, Nashville reporter Karin Miller says it still took her more than half a year to get over her fears and decide to have in vitro fertilization (IVF) last spring.

    "After going to the doctor and hearing what was involved, I completely freaked out," Miller tells WebMD. "It was a really scary time. It took me six or seven months to decide to go through with it."

    Research suggests that for many women, the stress associated with infertility treatment rivals that of being treated for cancer. Fears and concerns associated with in vitro fertilization have long been suspected of influencing the success of IVF. Now a new study sheds light on which fears affect IVF success the most.

    Cost Tops the List

    Researchers at the University of California in San Diego found that concerns about the cost of treatment most directly affected its success or failure. Women who reported being extremely stressed about paying for IVF were 11 times less likely to have a baby as women who were unconcerned. And stress associated with missing work also appeared to influence outcome in a big way.

    "This is a very expensive procedure, and people often end up paying for it without the help of insurance," lead researcher Hillary Klonoff-Cohen, PhD, tells WebMD. "Nevertheless, we were surprised that financial concerns had such a huge impact on outcome."

    The study involved 151 infertile women undergoing either IVF or a similar assisted reproduction procedure known as GIFT. The UCSD researchers developed a questionnaire to measure stress prior to treatment. They also recorded treatment endpoints like the number of eggs retrieved and fertilized, the number of pregnancies achieved, and the number of babies born.

    Although financial concerns had the most impact on outcome, women who worried about the medical aspects of treatment had 20% fewer eggs retrieved and 19% fewer eggs fertilized than those who expressed few concerns. The findings are reported in the April issue of the journal Fertility and Sterility.

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