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Marriage Stress Affects Infertility Treatment

Researchers Say Infertility-Related Stress Affects Chances of Pregnancy
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June 24, 2005 -- Ask any couple who has been through it and they will tell you there is little as stressful as wanting a baby and not being able to have one.

Infertility-related stress is known to take its toll on relationships, and now a new study shows it can also affect the success of fertility treatments.

Researchers reported that the stress of infertility on marriages was a stronger predictor of treatment failure than personal stress or infertility-related strains on other relationships.

Women who reported the most marital stress required more assisted reproduction cycles to get pregnant than women who reported less stress in their marriages, researcher Jacky Boivin, PhD, tells WebMD.

"The bottom line is that if infertility is causing a lot of stress in a partnership it could very well have an impact on whether the woman gets pregnant or not," Boivin says.

She says she did not believe stress played a significant role in infertility until recently, but the mounting evidence in favor of a link was impossible to ignore. She makes it clear, however, that biologic factors such as age and embryo quality are much more important in the success or failure of infertility treatments than stress.

Male Stress Mattered

The study is one of the largest ever to examine the role of stress on the success or failure of infertility treatments.

Boivin and colleague Lone Schmidt, PhD, followed roughly 800 Danish couples undergoing infertility treatments. All of the participants completed questionnaires at the beginning of the study to assess stress levels. The researchers then looked at pregnancy rates one year later.

During the one-year study period:

  • 71% of couples required 1 or 2 infertility treatment cycles
  • 26% had 3 to 5 cycles
  • 2% had more than 5 cycles

Roughly 60% of couples achieved an ongoing pregnancy or live birth and 40% did not.

Couples who did not achieve a pregnancy tended to be older than those who did, and they had been infertile longer and had more treatment cycles during the study.

While stress in men was an independent predictor of treatment success, the impact was much smaller than the impact seen in women. Boivin says the finding suggests that infertility-related stresses compromise sperm quality or other factors associated with male fertility.

"It has been thought that it was all about the woman and what is going on with her psyche," Boivin says. "But this suggests that the same stresses that affect female fertility can affect male fertility."

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