ICSI Male Infertility Treatment Up
Dramatic 5-Fold Increase Coupled With IVF During Last Decade
WebMD News Archive
IVF, ICSI, and Male Infertility continued...
While use of IVF roughly doubled over the decade -- from 45,900 fresh-embryo
cycles in 1995 to 89,500 in 2004 -- more than five times as many ICSI
procedures were being done in the last year of the observation period than in
The researchers found increasing use of ICSI relative to the percentage of
couples with a diagnosis of male infertility in both states with and without
mandated insurance coverage for infertility.
They also found an increase in the overall number of infertility clinics and
the number of pregnancies and live births achieved in patients undergoing
ICSI Indications Growing
Jain says some clinics now use ICSI routinely in couples who have failed
prior IVF attempts or in those with few or poor-quality eggs, even when semen
measurements are normal. He adds that a few clinics even advocate the routine
use of ICSI for all IVF attempts.
Society for Assisted Reproductive Technology President David Grainger, MD,
says there is little evidence that the practice improves success rates for
couples without a diagnosis of male infertility.
“I can find very little medical justification for performing ICSI 100% of
the time,” he says.
He says the report raises legitimate questions about the increasing use of
ICSI, but he adds that limitations in the surveillance data used in the study
make it difficult to draw conclusions about the frequency of use in men with
“Generally patients have more than one diagnosis, and that may not be
reflected in the reporting,” he says. “Diagnosis with regard to IVF is not
usually inaccurate, but it is often incomplete.”
- Struggling with male
infertility issues? Pose your questions to our WebMD expert, Sheldon Marks,
MD, on the Male Factor Infertility message board.