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Medical Reference Related to Lung Cancer

  1. Non-Small Cell Lung Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - nci_ncicdr0000062956-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Non-Small Cell Lung Cancer Treatment

  2. Non-Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (05 / 30 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Stages IA and IB NSCLC TreatmentAdded text to state that a substantial number of patients are ineligible for standard surgical resection because of comorbid conditions that are associated with unacceptably high perioperative risk; observation and radiation therapy may be considered for these patients (cited McGarry et al., Lanni et al., and Grutterset al. as reference 22, reference 23, and reference 24, respectively). Also added text to state that nonrandomized observation studies comparing treatment outcomes associated with resection, radiation therapy, and observation have demonstrated shorter survival times and higher mortality for patients treated with observation only, there are a number of approaches to delivery of radiation therapy, and there are limited reliable data from comparative

  3. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview for Small Cell Lung Cancer

    Chemotherapy and radiation therapy have been shown to improve survival for patients with small cell lung cancer (SCLC).ChemotherapyChemotherapy improves the survival of patients with limited-stage disease (LD) or extensive-stage disease (ED), but it is curative in only a minority of patients.[1,2] Because patients with SCLC tend to develop distant metastases, localized forms of treatment, such as surgical resection or radiation therapy, rarely produce long-term survival.[3] With incorporation of current chemotherapy regimens into the treatment program, however, survival is prolonged, with at least a fourfold to fivefold improvement in median survival compared with patients who are given no therapy. The combination of platinum and etoposide is the most widely used standard chemotherapeutic regimen.[4,5,6][Level of evidence: 1iiA] No consistent survival benefit has resulted from platinum versus nonplatinum combinations, increased dose intensity or dose density, altered mode of

  4. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - About This PDQ Summary

    About PDQPhysician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish.PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government's center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.Purpose of This SummaryThis PDQ cancer information summary has current

  5. Lung Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Changes to This Summary (08 / 02 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Description of the EvidenceAdded Spira et al. as reference 4.Added Lissowska et al. as reference 23.Added Straif et al. as reference 27.Added Gray et al. as reference 32.Added text evidence indicating an association between constituents of ambient air pollution and increased lung cancer mortality continues to strengthen, with reports from Asia and New Zealand documenting increased risks with exposure to measures of particulate matter, sulfur dioxide, and nitrogen dioxide (cited Katanoda et al., Cao et al., and Hales et al. as references 37, 38, and 39, respectively).Added World Cancer Research Fund/American Institute for Cancer Research as reference 40.This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary

  6. Lung Cancer Screening (PDQ®): Screening - Patient Information [NCI] - nci_ncicdr0000258019-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Lung Cancer Screening

  7. Non-Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Non-Small Cell Lung Cancer (NSCLC)

    NSCLC is any type of epithelial lung cancer other than small cell lung cancer (SCLC). The most common types of NSCLC are squamous cell carcinoma,large cell carcinoma,and adenocarcinoma,but there are several other types that occur less frequently,and all types can occur in unusual histologic variants. Although NSCLCs are associated with cigarette smoke,adenocarcinomas may be found in ...

  8. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Small Cell Lung Cancer

    For more information from the National Cancer Institute about small cell lung cancer, see the following:Lung Cancer Home PageWhat You Need to Know About™ Lung CancerLung Cancer PreventionLung Cancer ScreeningDrugs Approved for Small Cell Lung CancerSmoking Home Page (Includes help with quitting)Cigarette Smoking: Health Risks and How to QuitSmoking in Cancer CareSecondhand Smoke and CancerFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For Survivors/Caregivers/Advocates

  9. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Recurrent Small Cell Lung Cancer

    Recurrent small cell lung cancer is cancer that has recurred (come back) after it has been treated. The cancer may come back in the chest, central nervous system, or in other parts of the body.

  10. Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Malignant Mesothelioma

    Histologically, these tumors are composed of fibrous or epithelial elements or both. The epithelial form occasionally causes confusion with peripheral anaplastic lung carcinomas or metastatic carcinomas. Attempts at diagnosis by cytology or needle biopsy of the pleura are often unsuccessful. It can be especially difficult to differentiate mesothelioma from adenocarcinoma on small tissue specimens. Thoracoscopy can be valuable in obtaining adequate tissue specimens for diagnostic purposes.[1] Examination of the gross tumor at surgery and use of special stains or electron microscopy can often help. The special stains reported to be most useful include periodic acid-Schiff diastase, hyaluronic acid, mucicarmine, CEA, and Leu M1.[2] Histologic appearance seems to be of prognostic value, and most clinical studies show that patients with epithelial mesotheliomas have a better prognosis than those with sarcomatous or mixed histology mesotheliomas.[2,3,4]References: Boutin C, Rey F:

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