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Lung Cancer Health Center

Medical Reference Related to Lung Cancer

  1. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Options by Stage

    A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Occult Non-Small Cell Lung CancerTreatment of occult non-small cell lung cancer depends on the stage of the disease. Occult tumors are often found at an early stage (the tumor is in the lung only) and sometimes can be cured by surgery.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with occult non-small cell lung cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.Stage 0 (Carcinoma in Situ)Treatment of stage 0 may include the following:Surgery (wedge resection or segmental

  2. Lung Cancer Screening - About This PDQ Summary

    Purpose of This SummaryThis PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of non-small cell lung cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.Reviewers and UpdatesThis summary is reviewed regularly and updated as necessary by the PDQ Adult Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH). Board members review recently published articles each month to determine whether an article should:be discussed at a meeting,be cited with text, orreplace or update an existing article that is already cited.Changes to the summaries are made through a consensus

  3. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stages IIA and IIB NSCLC Treatment

    Standard Treatment Options for Stages IIA and IIB NSCLCStandard treatment options for stages IIA NSCLC and IIB NSCLC include the following:Surgery.Neoadjuvant chemotherapy.Adjuvant chemotherapy.Radiation therapy.Adjuvant radiation therapy has not been show to improve outcomes in patients with stages II NSCLC.SurgerySurgery is the treatment of choice for patients with stage II NSCLC. A lobectomy, pneumonectomy, or segmental resection, wedge resection, or sleeve resection may be performed as appropriate. Careful preoperative assessment of the patient's overall medical condition, especially the patient's pulmonary reserve, is critical in considering the benefits of surgery. Despite the immediate and age-related postoperative mortality rate, a 5% to 8% mortality rate with pneumonectomy or a 3% to 5% mortality rate with lobectomy can be expected. Evidence (surgery):The Cochrane Collaboration group reviewed 11 randomized trials with a total of

  4. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  5. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062825-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at or call 1-800-4-CANCER.Lung Cancer Prevention

  6. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (11 / 02 / 2012)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. Changes were made to this summary to match those made to the health professional version.

  7. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Malignant Mesothelioma Treatment

    Prognosis in this disease is difficult to assess consistently because there is great variability in the time before diagnosis and the rate of disease progression. In large retrospective series of pleural mesothelioma patients,important prognostic factors were found to be:[ 1,2 ] Stage. Age. Performance status. Histology. Various surgical procedures may be possible in selected patients,...

  8. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (02 / 27 / 2014)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Description of the EvidenceAdded Spira et al. as reference 4.Added Lissowska et al. as reference 23.Added Straif et al. as reference 27.Added Gray et al. as reference 32.Added text evidence indicating an association between constituents of ambient air pollution and increased lung cancer mortality continues to strengthen, with reports from Asia and New Zealand documenting increased risks with exposure to measures of particulate matter, sulfur dioxide, and nitrogen dioxide (cited Katanoda et al., Cao et al., and Hales et al. as references 37, 38, and 39, respectively).Added World Cancer Research Fund/American Institute for Cancer Research as reference 40.This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary

  9. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Limited-Stage Small Cell Lung Cancer Treatment

    Standard Treatment Options for Patients With Limited-Stage Small Cell Lung Cancer (SCLC)Standard treatment options for patients with limited-stage SCLC include the following:Chemotherapy and radiation therapy.Combination chemotherapy alone.Surgery followed by chemotherapy or chemoradiotherapy.Prophylactic cranial irradiation.Chemotherapy and radiation therapyCombined-modality treatment with etoposide and cisplatin with thoracic radiation therapy (TRT) is the most widely used treatment for patients with limited-stage disease (LD) SCLC.Evidence (combined modality treatment):Survival. The following results have been reported in clinical trials:Mature results of prospective randomized trials suggest that combined-modality therapy produces a modest but significant improvement in survival of 5% at 3 years compared with chemotherapy alone.[1,2,3][Level of evidence: 1iiA]Clinical trials have consistently achieved median survivals of 18 to 24 months and 40% to 50% 2-year survival

  10. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage IIIB NSCLC Treatment

    Based on the Surveillance, Epidemiology, and End Registry, the estimated incidence of stage IIIB NSCLC is 17.6%.[1] The anticipated 5-year survival for the vast majority of patients who present with clinical stage IIIB NSCLC is 3% to 7%.[2] In small case series, selected patients with T4, N0-1 disease, solely as the result of satellite tumor nodule(s) within the primary lobe, have been reported to have 5-year survival rates of 20%.[3,4][Level of evidence: 3iiiA]Standard Treatment Options for Stage IIIB NSCLCStandard treatment options for stage IIIB NSCLC include the following:Sequential or concurrent chemotherapy and radiation therapy.Chemotherapy followed by surgery (for selected patients).Radiation therapy alone.For treatment of locally advanced unresectable tumor in patients who are not candidates for chemotherapy.For patients requiring palliative treatment.In general, patients with stage IIIB NSCLC do not benefit from surgery alone and are best managed

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