Skip to content
My WebMD Sign In, Sign Up

Lung Cancer Health Center

Font Size

Lung Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Overview

continued...

Interventions Associated With an Increased Risk of Lung Cancer

Beta-carotene supplementation in current smokers

Based on solid evidence, high-intensity smokers who take pharmacologic doses of beta-carotene have an increased lung cancer incidence and mortality that is associated with taking the supplement.

Magnitude of Effect: Increased risk, small magnitude.

Study Design: Two randomized controlled trials with consistent results.
Internal Validity: Good.
Consistency: Good.
External Validity: Good.

Interventions That Do Not Decrease Risk of Lung Cancer

Beta-carotene in nonsmokers

Based on solid evidence, nonsmokers who take pharmacological doses of beta-carotene do not experience significantly different lung cancer incidence or mortality compared with taking a placebo.

Magnitude of Effect: No substantive effect.

Study Design: Randomized controlled trial.
Internal Validity: Good.
Consistency: Good.
External Validity: Fair.

Vitamin E/Tocopherol

Based on solid evidence, taking vitamin E supplements does not affect the risk of lung cancer.

Magnitude of Effect: Strong evidence of no association.

Study Design: Randomized controlled trials.
Internal Validity: Good.
Consistency: Fair.
External Validity: Good.

References:

  1. Pinsky PF: Racial and ethnic differences in lung cancer incidence: how much is explained by differences in smoking patterns? (United States). Cancer Causes Control 17 (8): 1017-24, 2006.
1|2|3
1|2|3

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Today on WebMD

lung cancer overview slideshow
SLIDESHOW
what is your cancer risk
HEALTH CHECK
 
Using GPS to Detect Lung Cancer
VIDEO
mans hand putting out cigarette
Article
 
15 Cancer Symptoms Men Ignore
FEATURE
Lung Cancer Risks Myths and Facts
SLIDESHOW
 
cancer fighting foods
SLIDESHOW
Improving Lung Cancer Survival Targeted Therapy
VIDEO
 
Lung Cancer Surprising Differences Between Sexes
VIDEO
Pets Improve Your Health
SLIDESHOW
 
Vitamin D
SLIDESHOW
Lung Cancer Surgery Options
VIDEO
 

WebMD Special Sections