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Nasal Potential Difference Test for Cystic Fibrosis - Topic Overview

The nasal potential difference test (nasal PD test) measures how well salts (sodium and chloride) flow across the mucous membranes in the nose. This type of test can be helpful when the results of a sweat test or a genetic test are not clear.

In this test, electrodes are placed inside the nose and liquids are run through the nose. There is also a needle placed in the forearm that connects to a machine. Because this test can be uncomfortable, your child may need medicine to help him or her relax before having the test.

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This test is not used very often because it can be difficult to do and because it is not available in many places.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: July 18, 2013
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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