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Nasal Potential Difference Test for Cystic Fibrosis - Topic Overview

The nasal potential difference test (nasal PD test) measures how well salts (sodium and chloride) flow across the mucous membranes in the nose. This type of test can be helpful when the results of a sweat test or a genetic test are not clear.

In this test, electrodes are placed inside the nose and liquids are run through the nose. There is also a needle placed in the forearm that connects to a machine. Because this test can be uncomfortable, your child may need medicine to help him or her relax before having the test.

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Lung Diseases Overview

Lung diseases are some of the most common medical conditions in the world. Tens of millions of people suffer from lung disease in the U.S. Smoking, infections, and genetics are responsible for most lung diseases. The lungs are part of a complex apparatus, expanding and relaxing thousands of times each day to bring in oxygen and expel carbon dioxide. Lung disease can result from problems in any part of this system.

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This test is not used very often because it can be difficult to do and because it is not available in many places.

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WebMD Medical Reference from Healthwise

Last Updated: June 15, 2011
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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