The lungs are usually the first area to be affected by sarcoidosis: 9 of 10 people with sarcoidosis have some type of lung involvement. Pulmonary sarcoidosis can be serious, leading to the formation of scar tissue (fibrosis) in the lungs. This complication can interfere with breathing.
Recommended Related to Lung Disease/Respiratory Problems
Bronchitis is a respiratory disease in which the mucus membrane in the lungs' bronchial passages becomes inflamed.
As the irritated membrane swells and grows thicker, it narrows or shuts off the tiny airways in the lungs, resulting in coughing spells that may be accompanied by phlegm and breathlessness.
The disease comes in two forms: acute (lasting from one to three weeks) and chronic (lasting at least 3 months of the year for two years in a row).
People with asthma may also have asthmatic bronchitis,...
Other symptoms include skin rashes or red bumps (erythema nodosum) on the legs. In about 20% to 30% of cases, sarcoidosis affects the eyes, causing redness, tearing, or, rarely, more severe complications, such as cataracts, glaucoma, and blindness. Sarcoidosis can also affect the brain and nerves, heart, liver, and various hormone-producing glands.
The granulomas or clumps of cells that characterize sarcoidosis may occasionally be associated with high levels of calcium in the blood and urine. Too much calcium in the urine may lead to kidney stones.
The course of sarcoidosis also varies among individuals. Usually, patients who experience more generalized symptoms, such as weight loss and fatigue, develop a mild form of the disease. Patients suffering from shortness of breath and skin rashes may develop more chronic, severe sarcoidosis. Race also seems to play a role; Caucasians are more likely to develop a mild form of the disease, while African-Americans tend to develop the more chronic, severe form.