Fever is often a part of lupus. For some people with lupus, an intermittent (coming and going) or continuous low-grade fever may be normal. Other people, especially those on large doses of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or corticosteroids, may not have fever at all because these drugs may mask a fever.
If you have lupus, you may be more vulnerable to certain infections than are other people without lupus. In addition, you may be more prone to infection if you are taking any immunosuppressive drugs for your lupus. Be alert to a temperature that is new or higher than normal for you, because it could be a sign of a developing infection or a lupus flare.
Lupus can affect just about any part of your body, but medicine can help prevent and ease problems. There are also steps you can take on your own to avoid the effects of lupus on your heart, skin, kidneys, eyes, and other areas.
Take your temperature at least once a day (or more often if needed) to determine what a "normal" temperature is for you.
Take your temperature and watch for a fever any time you feel chills or do not feel well.
Call your doctor immediately if you have a new or higher-than-normal temperature.
Even if you don't have a fever, don't hesitate to call your doctor if you do not feel well in any way, particularly if you are taking aspirin, NSAIDs, or a corticosteroid. Signs of infection other than a fever include unusual pain, cramping or swelling, a headache with neck stiffness, cold or flu symptoms, trouble breathing, nausea, vomiting, diarrhea, or changes in urine or stool.
"The National Institute of Arthritis and Musculoskeletal and Skin
Diseases of The National Institutes of Health. Fever and Lupus. Last revised,
January 26, 1999. (Online)