Lupus: Criteria for Diagnosis - Topic Overview
The following criteria are used to distinguish lupus (systemic lupus erythematosus, or SLE) from other autoimmune and rheumatic diseases.
A person with 4 of these 11 conditions can be classified as having lupus. These conditions may be present all at once, or they may appear in succession over a period of time.1
- Butterfly (malar ) rash on cheeks
- Rash on face, arms, neck, torso (discoid rash)
Skin rashes that result from exposure to sunlight or ultraviolet light (photosensitivity)
Mouth or nasal sores (ulcers), usually painless
Joint swelling, stiffness, pain involving two or more joints (arthritis)
Inflammation of the membranes surrounding the lungs (pleuritis) or heart (pericarditis)
- Abnormalities in urine, such as increased protein or clumps of red blood cells or kidney cells, called cell casts
Nervous system problems, such as seizures or psychosis, without known cause
- Problems with the blood, such as reduced numbers of red blood cells (anemia), platelets, or white blood cells
- Laboratory tests showing increased autoimmune activity (antibodies against normal tissue)
- Positive antinuclear antibody (ANA) test
WebMD Medical Reference from Healthwise
September 09, 2014
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Lupus: Criteria for Diagnosis Topics