Stem cell transplantation is the replacement of damaged
bone marrow cells with healthy cells, or stem cells. It is generally done after
powerful drugs have been used to wipe out the damaged immune system
Stem cells are immature cells that are produced
in the bone marrow. They can divide to produce more stem cells or mature into
red blood cells, white blood cells, and platelets.
Doctors once advised women with lupus not to get pregnant due to the potential risks to mother and baby. But while pregnancy with lupus still carries its own set of risks, most women with lupus can safely become pregnant and have healthy babies.
If you have lupus and are thinking about getting pregnant, here's what you need to know about the possible risks and complications. Here's also what you and your doctor can do to help ensure the best outcome for you and your baby.
Stem cell transplantation has serious
risks. After a person's stem cells have been collected from the bloodstream,
they are returned to the bloodstream along with a stem cell growth factor. If
successful, the stem cells help the bone marrow return to a healthy state.
But during the two weeks that the
immune system requires to become strong again, the
body is extremely vulnerable to life-threatening infection.
Small studies of stem cell transplantation for people with severe lupus have shown that it may help some people but it also has serious side effects.1 This procedure is considered a high-risk, expensive,
and experimental treatment for lupus.
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This information is produced and provided by the National
Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National
Institute via the Internet web site at http://
.gov or call 1-800-4-CANCER.
WebMD Medical Reference from Healthwise
May 10, 2012
This information is not intended to replace the advice of a doctor.
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