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Melanoma/Skin Cancer Health Center

Medical Reference Related to Melanoma Skin Cancer

  1. Intraocular (Uveal) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Intraocular (Uveal) Melanoma

    Primary intraocular melanomas originate from melanocytes in the uveal tract.[1] Four distinct cellular types are recognized in intraocular melanoma (revised Callender classification):[2]Spindle-A cells (spindle-shaped cells with slender nuclei and lacking visible nucleoli). Spindle-B cells (spindle-shaped cells with larger nuclei and distinct nucleoli).Epithelioid cells (larger polygonal cells with one or more prominent nucleoli).Intermediate cells (similar to but smaller than epithelioid cells).Most primary intraocular melanomas contain variable proportions of epithelioid, spindle-A, and spindle-B cells (mixed-cell melanomas). Pure epithelioid-cell primary melanomas are infrequent (approximately 3% of cases).[1] In the Collaborative Ocular Melanoma Study, mixed-cell type melanomas predominated (86% of cases).[3]References: Klintworth GK, Scroggs MW: The eye and ocular adnexa. In: Sternberg SS, ed.: Diagnostic Surgical Pathology. Philadelphia, Pa: Lippincott Williams & Wilkins, 1999,

  2. Skin Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Skin Cancer

    For more information from the National Cancer Institute about skin cancer,see the following: Skin Cancer Home Page What You Need to Know About™ Skin Cancer Skin Cancer Prevention Skin Cancer Screening Cryosurgery in Cancer Treatment: Questions and Answers Lasers in Cancer Treatment: Questions and Answers Photodynamic Therapy for Cancer: Questions and Answers For general cancer information and ...

  3. Intraocular (Eye) Melanoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Intraocular (Eye) Melanoma

    Treatment of iris melanoma may include the following: Watchful waiting. Surgery (local tumor resection or enucleation). Plaque radiation therapy. Ciliary Body Melanoma Treatment of tumors in the ciliary body and choroid may include the following: Plaque r

  4. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Melanoma

    Related Summaries Note: Other PDQ summaries containing information related to melanoma include the following: Skin Cancer Prevention Skin Cancer Screening Skin Cancer Treatment Statistics Note: Estimated new cases and deaths from melanoma in the United States in 2010:[ 1 ] New cases: 68,130. Deaths: 8,700. Melanoma is a malignant tumor of melanocytes,which are the cells that make the pigment ...

  5. Melanoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Melanoma

    After melanoma has been diagnosed,tests are done to find out if cancer cells have spread within the skin or to other parts of the body. The process used to find out whether cancer has spread within the skin or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan ...

  6. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062917-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Melanoma Treatment

  7. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - About This PDQ Summary

    PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about the treatment of melanoma. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND UPDATES This ...

  8. Skin Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview

    There are different types of treatment for patients with nonmelanoma skin cancer and actinic keratosis. Different types of treatment are available for patients with nonmelanoma skin cancer and actinic keratosis. Some treatments are standard (the currently used treatment),and some are being tested in clinical trials. Before starting treatment,patients may want to think about taking part in a ...

  9. Skin Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - nci_ncicdr0000062802-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Skin Cancer Prevention

  10. Intraocular (Uveal) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview

    Role of ObservationIris melanomas have relatively good outcomes with a 5-year survival rate of more than 95%. They are predominantly of the spindle-cell type and are usually smaller in size than posterior melanomas because of earlier detection. Conservative management is generally advocated whenever possible, but surgical intervention may be justified with unequivocal tumor growth or with extensive disease at initial examination.The management of small choroidal melanomas is controversial, and it is not clear whether treatment of small tumors prevents metastasis.[1] The natural history of small choroidal melanoma is poorly understood. Small, pigmented, choroidal lesions cannot always be differentiated reliably on examination. Growth is a presumed indicator of malignant potential.[2] The likelihood of progression from the time of diagnosis to the time when tumor growth warrants treatment has not been well characterized. Some ophthalmologists advocate

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