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Melanoma/Skin Cancer Health Center

Medical Reference Related to Melanoma Skin Cancer

  1. Intraocular (Uveal) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Intraocular (Uveal) Melanoma Treatment

    Incidence and MortalityMelanoma of the uveal tract (iris, ciliary body, and choroid), though rare, is the most common primary intraocular malignancy in adults. The mean age-adjusted incidence of uveal melanoma in the United States is approximately 4.3 new cases per million population, with no clear variation by latitude. Males have a higher incidence than females (4.9 vs. 3.7 per million).[1] The age-adjusted incidence of this cancer has remained stable since at least the early 1970s.[1,2] U.S. incidence rates are low compared with the rates of other reporting countries, which vary from about 5.3 to 10.9 cases per million. Some of the variation may be the result of differences in inclusion criteria and methods of calculation.[1]Uveal melanoma is diagnosed mostly at older ages, with a progressively rising, age-specific, incidence rate that peaks near the age of 70 years.[3] Host susceptibility factors associated with the development of this cancer include:[2,3,4]Caucasian race.Light

  2. Genetics of Skin Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Rare Skin Cancer Syndromes

    Brooke-Spiegler Syndrome,Multiple Familial Trichoepithelioma,and Familial Cyndromatosis Brooke-Spiegler Syndrome (BSS),familial cylindromatosis,and multiple familial trichoepithelioma (MFT) are all autosomal dominant syndromes with overlapping clinical characteristics with allelic variance.[ 1 ] Features of BSS include multiple skin appendage tumors such as cylindromas (tumors arising in the ...

  3. Metastatic Squamous Neck Cancer with Occult Primary Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Metastatic Squamous Neck Cancer with Occult Primary

    For more information from the National Cancer Institute about metastatic squamous neck cancer with occult primary,see the following: Carcinoma of Unknown Primary Home Page Head and Neck Cancer Home Page Oral Complications of Chemotherapy and Head/Neck Radiation Metastatic Cancer For general cancer information and other resources from the National Cancer Institute,see the following: What You ...

  4. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - About This PDQ Summary

    PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about the treatment of melanoma. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND UPDATES This ...

  5. Intraocular (Uveal) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Medium and Large Choroidal Melanoma

    Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Enucleation remains the standard therapy for most large choroidal melanomas and

  6. Melanoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

    Sources of further information about Melanoma Treatment.

  7. Skin Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Skin Cancer

    For more information from the National Cancer Institute about skin cancer,see the following: Skin Cancer Home Page What You Need to Know About™ Skin Cancer Skin Cancer Prevention Skin Cancer Screening Cryosurgery in Cancer Treatment: Questions and Answers Lasers in Cancer Treatment: Questions and Answers Photodynamic Therapy for Cancer: Questions and Answers For general cancer information and ...

  8. Intraocular (Eye) Melanoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Changes to This Summary (01 / 11 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. Changes were made to this summary to match those made to the health professional version and images were added.

  9. Skin Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Who is at Risk?

    Note: Separate PDQ summaries on Skin Cancer Screening,Skin Cancer Treatment,and Levels of Evidence for Cancer Screening and Prevention Studies are also available. Individuals whose skin freckles,tans poorly,or burns easily after sun exposure are particularly susceptible to developing skin cancer.[ 1 ] Observational and analytic epidemiologic studies have consistently shown that increased ...

  10. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (04 / 012013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.General Information About MelanomaUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).Cellular and Molecular Classification of MelanomaAdded Carvajal et al. as reference 6.Stage IV and Recurrent MelanomaRevised text of the signal transduction inhibitors treatment option to include BRAF inhibitors.Added text to include a treatment option that states that clinical trials should be considered because of the advances in the development of novel agents and combinations of agents designed to reverse or interrupt aberrant molecular pathways that support tumor growth.Added text to state that studies to date indicate that both BRAF and MEK (mitogen-activated ERK-[extracellular signal-regulated kinase] activating kinase) inhibitors can

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