Skip to content
My WebMD Sign In, Sign Up

Melanoma/Skin Cancer Health Center

Medical Reference Related to Melanoma Skin Cancer

  1. Skin Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary,please send them to Cancer.gov through the Web site's Contact Form.

  2. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (04 / 012013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.General Information About MelanomaUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).Cellular and Molecular Classification of MelanomaAdded Carvajal et al. as reference 6.Stage IV and Recurrent MelanomaRevised text of the signal transduction inhibitors treatment option to include BRAF inhibitors.Added text to include a treatment option that states that clinical trials should be considered because of the advances in the development of novel agents and combinations of agents designed to reverse or interrupt aberrant molecular pathways that support tumor growth.Added text to state that studies to date indicate that both BRAF and MEK (mitogen-activated ERK-[extracellular signal-regulated kinase] activating kinase) inhibitors can

  3. Intraocular (Uveal) Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Ciliary Body Melanoma

    Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Melanoma involving the ciliary body is a rare tumor that carries a poor ...

  4. Skin Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - About PDQ

    PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site.

  5. Melanoma Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Melanoma

    Melanoma is a disease in which malignant (cancer) cells form in the skin cells called melanocytes (cells that color the skin). Melanocytes are found throughout the lower part of the epidermis. They produce melanin,the pigment that gives skin its natural color. When skin is exposed to the sun,melanocytes produce more pigment,causing the skin to tan,or darken. The skin is the body’s largest ..

  6. Genetics of Skin Cancer (PDQ®): Genetics - Health Professional Information [NCI] - About This PDQ Summary

    PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about the genetics of skin cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND UPDATES This ...

  7. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular and Molecular Classification of Melanoma

    Following is a list of clinicopathologic cellular subtypes of malignant melanoma. These should be considered descriptive terms of historic interest only as they do not have independent prognostic or therapeutic significance. Superficial spreading.Nodular.Lentigo maligna.Acral lentiginous (palmar/plantar and subungual).Miscellaneous unusual types: Mucosal lentiginous (oral and genital).Desmoplastic.Verrucous.Molecular characterization of melanoma is an active area of research. Activating mutations in the BRAF (V-raf murine sarcoma viral oncogene homolog B1) gene, first reported in 2002, are the most frequent mutation in cutaneous melanoma. Approximately 40% to 60% of malignant melanomas harbor a single nucleotide transversion. The majority have a mutation that results in a substitution from valine to glutamic acid at position 600 BRAF (V600E); less frequent mutations include valine 600 to lysine or arginine residues (V600K/R).[1] Drugs that target this mutation by inhibiting BRAF are

  8. Melanoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Melanoma

    Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Stage II melanoma is defined by the following clinical stage groupings: T2b,...

  9. Skin Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Description of the Evidence

    Background Incidence and mortality There are three main types of skin cancer: basal cell carcinoma,squamous cell carcinoma (together with basal cell carcinoma referred to as nonmelanoma skin cancer),and melanoma. Basal cell carcinoma and squamous cell carcinoma are the most common forms of skin cancer but have substantially better prognoses than the less common,generally more aggressive ...

  10. Skin Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

Displaying 81 - 90 of 162 Articles << Prev Page 5 6 7 8 9 10 11 12 13 14 Next >>

Today on WebMD

Woman checking out tan lines
SLIDESHOW
Cancer Fighting Foods Slideshow
SLIDESHOW
 
what is your cancer risk
HEALTH CHECK
Could Caffeine Help Fight Skin Cancer
VIDEO
 

12 Ways to Protect Your Skin from Melanoma
ARTICLE
precancerous lesions slideshow
SLIDESHOW
 
Do You Know Your Melanoma ABCs
VIDEO
15 Cancer Symptoms Men Ignore
ARTICLE
 

screening tests for men
SLIDESHOW
Vitamin D
SLIDESHOW
 
Is That Mole Skin Cancer
VIDEO
Brilliant sun rays
Quiz
 

WebMD Special Sections