Sunscreen Use and Ultraviolet (UV) Radiation Avoidance
The evidence that interventions designed to reduce exposure to UV radiation by the use of sunscreen, protective clothing, or limitation of sun exposure time decrease the incidence of nonmelanoma skin cancer is inadequate. A randomized study suggested a possible reduction in incidence of squamous cell carcinomas (SCCs), but study design and analysis problems complicate interpretation of the results.[1,2]
Targeted therapy with inhibitors. These are medicines that inhibit, or prevent, cancer cells from growing by blocking signals in the cell. Inhibitors are only given if a gene test shows that a person has the BRAF gene change, or mutation.
Metastatic melanoma and melanoma that can't be removed with surgery may be treated with inhibitors.
Melanoma can come
back after treatment. This is called recurrent melanoma. All of the treatments mentioned above may be used for recurrent melanoma as well as:
Hyperthermic isolated limb perfusion. If the melanoma is on your arm or leg, chemotherapy medicine may be added to a warm solution and injected into the bloodstream of that arm or leg. The flow of blood to and from that limb is stopped for a short time so the medicine can go right to the tumor.
Medicines injected directly into the tumor.
Lasers to destroy the tumor.
If your melanoma can't be cured, your doctors will try to control symptoms, reduce complications, and keep you comfortable.
Your doctor may recommend that you join a clinical trial if one is available in your area. Clinical trials may offer the best treatment option for people who have metastatic cancer. Clinical trials study other treatments, such as combinations of chemotherapy, vaccines, and immunotherapies. They are also studying targeted therapy.
Regular follow-up appointments are
important after you have been diagnosed with melanoma.
Your doctor will set up a regular schedule of checkups that will happen less often as time goes on.
To learn more about specific treatments for melanoma, go to the National Cancer Institute's website at www.cancer.gov/cancertopics/types/melanoma.