The first step with skin cancer is to do a biopsy to be sure the skin problem is actually cancer. Once confirmed, many skin cancers can be surgically removed, frozen, or killed with radiation. Immunotherapy and chemotherapy are sometimes also used. Drugs such as interferon may help with advanced melanoma. Alternative treatments may help in alleviating treatment side effects, but they do not cure skin cancer. Dietary complementary treatments are being tested for effectiveness. Follow the links below to find WebMD's comprehensive coverage about how skin cancer is treated, what to expect from treatment, and much more.