Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Men's Health

Font Size

FDA Approves Gel to Treat Low Testosterone Levels


"In none of the partners of the individuals who were treated with testosterone were there any significant clinical problems," Swerdloff tells WebMD. "Because there is a potential for testosterone transfer, the recommendation is that patients shower before intimate contact or wear a shirt over the area to which the drug is applied. The testosterone is driven into the skin, so showering doesn't alter the effectiveness of the testosterone."

To assess the effectiveness of AndroGel, researchers studied 227 men with low testosterone levels. The men received either AndroGel in varying doses, or testosterone through a skin-patch delivery system. After 60 days, their blood levels of testosterone were checked and the doses were adjusted. Of the 129 men who were appropriately adjusted, 87% achieved normal levels of testosterone that were maintained for the remaining three months of the trial. In this and other trials, side effects were moderate but infrequent -- mostly skin reactions to the gel, including acne; prostate and urinary problems; and swelling.

"We were able to put the testosterone into the normal blood range in the majority of the people. It's simply a matter of adjusting the amount of gel that's applied. So everybody could be treated once a proper dosage [is] determined," Swerdloff says. The manufacturer recommends checking the blood two weeks after starting.

"The positive effects were on sexual drive and on mood," Swerdloff says. "People had less depressive symptoms. There was an improvement in the lean body mass and muscle strength. ... It was surprising to us that within six months of treatment, there was a significant increase of bone mineral density."

Swerdloff tells WebMD that there are many potential applications for testosterone. It is being studied in combination with other hormones as a male contraceptive. Many researchers are looking at giving androgen replacement therapy in men over 65. Testosterone may also one day be used in women to improve libido, or added to conventional hormonal therapy to help improve bone mineral density. AndroGel is only approved for men and has not been studied in those over age 65.

Today on WebMD

man coughing
Men shouldn’t ignore.
man swinging in hammock
And how to get out it.
shaving tools
On your shaving skills.
muscular man flexing
Four facts that matter.
Food Men 10 Foods Boost Male Health
Thoughtful man sitting on bed
Man taking blood pressure
doctor holding syringe
Condom Quiz
man running
older couple in bed