Low Testosterone, More Men's Fractures
Low Testosterone Tied to Osteoporosis Bone Fractures in Men Over 60
Jan. 15, 2008 -- Low testosterone levels may make men over 60 more likely to
suffer an osteoporosis bone fracture.
Osteoporosis, in which bones get dangerously thin, is most common among postmenopausal women. But it can
also strike men in advanced age.
"One third of all osteoporotic fractures occur in men," write
Christian Meier, MD, of Switzerland's University Hospital Basel, and
Meier's team analyzed data on 609 men older than 60 in Australia. The men
got a bone mineral density test and had their blood levels of testosterone
The men were followed for almost six years, on average. During that time,
113 men sustained at least one osteoporosis bone fracture.
Men with osteoporosis bone fractures were more likely than other men to have
had low testosterone levels at the study's start, regardless of other factors
including age, weight, bone mineral density, smoking, and calcium intake.
But the researchers caution that the observational study doesn't prove that
low testosterone causes bone fractures or osteoporosis in men. And they aren't
ready to recommend hormone therapy to help men avoid osteoporosis bone
If such therapies are proven safe and effective at preventing fractures in
healthy older men, "it is most likely to be justified only in those with
the most severe testosterone deficiency," Meier and colleagues write in the
Archives of Internal Medicine.