Penis Spray Makes Men Last Longer
1 Spritz 5 Minutes Before Sex Fights Premature Ejaculation, Studies Show
WebMD News Archive
Nov. 19, 2009 - An experimental penis spray, applied five minutes before
sex, helps men overcome premature ejaculation, new studies confirm.
The spray, dubbed PSD502, contains the anesthetics lidocaine and prilocaine.
But it doesn't deaden feeling, thanks to an ingredient in the spray that allows
it to rapidly penetrate the skin, says Ira Sharlip, MD, clinical professor of
urology a the University of California, San Francisco.
"It rarely causes a decrease in sensation in the penis because it is
absorbed so quickly," Sharlip tells WebMD. "In men using the product, the
incidence of penile anesthesia is 1% or 2%."
The drug also seems safe for men's female sex partners. Only about 0.5% of
female partners report decreased feeling in the vagina.
"There is some burning sensation in the vagina in about 5% of partners,"
Sharlip says. "It infrequently causes problems in female partners because
it is absorbed so quickly there is little left on the skin. The risk of
transfer is small."
Sharlip was one of three investigators presenting studies of PSD502 at this
week's meeting of the Sexual Medicine Society of North America Inc. in San
Diego. Sharlip and the other study presenters serve as consultants to Sciele
Pharma Inc., which acquired the rights to PSD502 from U.K.-based Plethora
The studies show that men using PSD502 are able to delay ejaculation about
five times longer. Sharlip's study found that men who ejaculated an average 36
seconds after vaginal penetration were able to delay ejaculation for over three
minutes after one month of PSD502 treatment, and for three minutes and 42
seconds after three months of treatment.
The findings confirm those of a
previous study reported earlier this year.
Premature ejaculation isn't just a problem for young, inexperienced teens.
Sharlip says it affects some 20% to 30% of men of all ages.
"A lot of men with PE just struggle and are very unhappy, although not
everyone who has PE is unhappy about it. But many men are very disturbed and
distressed by it," Sharlip says.
Many men suffering premature ejaculation are unable to delay ejaculation for
much more than half a minute. Some are unable delay long enough to achieve
vaginal penetration, making it difficult for them to father children.
Current treatments include off-label use of SSRI antidepressants, as delayed
ejaculation is a common side effect of these drugs. But the drugs must either
be taken daily -- increasing the risk of side effects -- or taken three to six
hours in advance of sexual activity.
"Sex is not always that predictable," Sharlip says.
There are also topical preparations. One that is commonly used is EMLA
cream, which, like PSD502, contains lidocaine and prilocaine. However, EMLA
must be used with a condom or washed off prior to sex.
"I think PSD502 will attract a lot of men particularly because it has a very
rapid onset of action," Sharlip says. "You put this stuff on and in five
minutes you have an effect."
Sharlip says that based on the studies reported today, he hopes PSD502 will
become available in a little more than a year's time.