Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Men's Health

Font Size

Treatment Shows Promise for Premature Ejaculation

Freezing Overactive Nerves Helped Men Last Longer in Small Study
WebMD Health News
Reviewed by Laura J. Martin, MD

Dec. 2, 2011 (Chicago) -- An experimental approach in which penile nerve tissue is frozen to knock out overactive nerves helped men with premature ejaculation last three times longer.

Researchers tested the technique on 24 men who hadn't been helped by standard treatments. They lasted an average of 110 seconds before ejaculation, or nearly two minutes, over the three months they were followed, compared with 36 seconds before treatment.

"That's about what you see with standard drug therapy," says researcher J. David Prologo, MD, assistant professor of interventional radiology at Case Western Reserve University’s School of Medicine in Cleveland. A time to ejaculation of more than two minutes is normal, he tells WebMD.

Its supporters say the technique, or a similar one involving heat therapy, could someday become a standard treatment for the condition.

But other experts tell WebMD that questions about the long-term consequences remain. Also unknown: whether men would opt for the treatment.

The findings were presented here at the annual meeting of the Radiological Society of North America. Prologo consults for Galil Medical, which funded the study.

Common Sex Problem for Men

Premature ejaculation affects 20% to 38% of men, making it among the most common forms of male sexual dysfunction worldwide.

Treatment options include certain antidepressants such as Celexa (citalopram), Paxil (paroxetine), Prozac (fluoxetine), and Zoloft (sertraline), as well as anesthetic ointments and cream, and behavioral therapies.

But many men aren't helped by the treatments, Prologo says.

The new technique involves inserting a tiny, hollow needle into the skin near the belly button.

Using computerized imaging for guidance, the doctor snakes it down to one of the two dorsal penile nerves. Overactivity of these nerves has been implicated as a cause of premature ejaculation.

"Then we knock out the nerve by freezing it," Prologo says.

"It's not painful, though some men feel a cold sensation," he says.

The procedure takes about 45 minutes, and men can go home the same day. While still experimental, Prologo estimates the cost at $3,500.

Repeat Injections May Be Needed

After the procedure, men were asked five questions relating to their sexual satisfaction. All improved on at least one sexual-related symptom.

Today on WebMD

man coughing
Men shouldn’t ignore.
man swinging in hammock
And how to get out it.
shaving tools
On your shaving skills.
muscular man flexing
Four facts that matter.
Food Men 10 Foods Boost Male Health
Thoughtful man sitting on bed
Man taking blood pressure
doctor holding syringe
Condom Quiz
man running
older couple in bed