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Klinefelter Syndrome - Topic Overview

How is it treated?

Males with Klinefelter syndrome can be given testosterone, a hormone needed for sexual development. If treatment is started around the age of puberty, it can help boys have more normal body development.

Testosterone is given by injection or through a skin patch or gel. The treatment usually continues throughout a man's life but does not help infertility.

Speech therapy and educational support can help boys who have language or learning problems.

If a man with Klinefelter wants to have children, he may be able to have his sperm collected through testicular sperm extraction (TEST). During TEST, sperm are obtained using a thin needle inserted into the testicle or through a small cut made in the testicle. Normal sperm are identified and then used for in vitro fertilization.

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