Skip to content

Menopause Health Center

Select An Article

Menopause Causes

    Font Size

    Menopause occurs naturally when a woman's ovaries run out of functioning eggs. At the time of birth, most females have about 1 to 3 million eggs, which are gradually lost throughout a woman's life. By the time of a girl's first menstrual period, she has an average of about 400,000 eggs. By the time of menopause, a woman may have fewer than 10,000 eggs. A small percentage of these eggs are lost through normal ovulation (the monthly cycle). Most eggs die off through a process called atresia.

    Normally, FSH, or follicle-stimulating hormone (a reproductive hormone), is the substance responsible for the growth of ovarian follicles (eggs) during the first half of a woman's menstrual cycle. As menopause approaches, the remaining eggs become more resistant to FSH, and the ovaries dramatically reduce their production of a hormone called estrogen.

    Estrogen affects many parts of the body, including the blood vessels, heart, bone, breasts, uterus, urinary system, skin, and brain. Loss of estrogen is believed to be the cause of many of the symptoms associated with menopause. At the time of menopause, the ovaries also decrease their production of testosterone -- a hormone involved with sex drive.

    Recommended Related to Menopause

    Menopause: Is There Life Beyond Hormone Replacement Therapy?

    Menopause gets a bad rap, but there is an upside. A major, essential, glorious one, says Renzie Richardson, a 51-year-old human resources consultant from Cumming, Ga. “I was definitely happy not to have a period anymore. That in itself was a celebration.” Still, the wider ramifications of going through The Change threw her for a loop. “I thought the period was gone -- that was it. But now you’ve got all these other symptoms you have to deal with.” Richardson was taken by surprise by hot flashes,...

    Read the Menopause: Is There Life Beyond Hormone Replacement Therapy? article > >

    WebMD Medical Reference from eMedicineHealth

    Reviewed by Traci C. Johnson, MD, FACOG on July 13, 2014
    Next Article:

    Today on WebMD

    woman walking outdoors
    How to handle headaches, night sweats, and more.
    mature woman holding fan in face
    Symptoms and treatments.
    woman hiding face behind hands
    11 ways to keep skin bright and healthy.
    Is it menopause or something else?
    senior couple
    mature woman shopping for produce
    Alcohol Disrupting Your Sleep
    mature couple on boat
    mature woman tugging on her loose skin
    senior woman wearing green hat
    estrogen gene

    WebMD Special Sections