Menopause Health Center
Your Guide to Menopause
Menopause is the end of a woman's menstrual cycle and fertility and is a normal condition that all women experience as they age. It occurs when the ovaries no longer produce estrogen and progesterone, two necessary hormones for a woman's reproductive cycle to function.
Though it naturally occurs with age, menopause may also come on suddenly as a result of a surgical procedure, treatment of a disease, or illness. In these cases it is referred to as induced menopause.
When Do Women Usually Enter Menopause?
When menopause occurs naturally, it tends to take place anywhere between the ages of 40 and 58, with an average age of 51. But for some women it can occur as early as the late 30s, or as late as your 60s. When menopause occurs before 35, it is considered premature menopause, but just as menarche is genetically predetermined, so is menopause.
What Are the Symptoms of Menopause?
For many women who enter menopause, their menstrual cycle becomes irregular and then stops, and they don't have any other symptoms. But, for others, the decreasing levels of estrogen associated with menopause may cause more distressing symptoms that include:
- Mood swings
- Decreased sex drive
- Hot flashes
- Sweating
- Racing heart (palpitations)
- Headaches
- Vaginal dryness and soreness
- Trouble sleeping
- Bone thinning (osteoporosis)
These symptoms can last from a few months to up to 10 years.
What Are the Stages of Menopause?
Menopause is a gradual process. The events preceding and following menopause amount to a huge change for women both physically and socially. Physically, this process has four stages:
- Premenopause. Some experts feel that this term should include the entire reproductive period up to the final menstrual cycle whereas others consider it to refer to women on the cusp of menopause. Their periods have just started to get irregular, but they do not yet experience any classic menopausal symptoms such as hot flashes or vaginal dryness. A woman in premenopause is usually in her mid-to-late 40s. If your doctor tells you that you're premenopausal, you might want to ask him or her how he or she is using this term.
- Perimenopause. This term refers to women who are in the thick of menopause. Their cycles may be erratic, and they may begin to experience hot flashes and vaginal dryness. On average, women are about 47 when they hit the perimenopause stage.
- Menopause. This refers to your final menstrual period. You will not be able to pinpoint your final period until you've been completely free from periods for one year. Then, you count back to the last period you charted, and that date is the date of your menopause. Note: After more than one year of no menstrual periods due to menopause, any vaginal bleeding is now considered abnormal.
- Postmenopausal. This term refers to the last third of most women's lives, ranging from women who have been free of menstrual periods for at least one year to women celebrating their 100th birthday and beyond. In other words, once you're past menopause, you'll be referred to as postmenopausal for the rest of your life.
WebMD Medical Reference
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

