Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Mental Health Center

Font Size

Does Dopamine Explain Why Slackers Slack?

Researchers Find Brains of 'Go-Getters' Handle the Chemical Differently Than Do 'Slackers'
WebMD Health News
Reviewed by Laura J. Martin, MD

May 1, 2012 -- Don't have any motivation at work today? You may be able to blame your brain and its relationship with the chemical dopamine.

The way your brain handles dopamine may predict whether you are a hard worker or a slacker, new research suggests.

"If you look around at the people you know, yourself included, and think of the people always driven to work hard vs. the people who prefer to take it easy, what this study shows is that the range in motivation is in part due to how the dopamine system functions," says researcher Michael Treadway, PhD, a clinical fellow at McLean Hospital and Harvard Medical School.

The new research reflects and reinforces some previous research, Treadway says. The findings could have important implications to help treat conditions marked by decreased motivation, such as depression or attention deficit hyperactivity disorder (ADHD), he tells WebMD.

The study is published in the Journal of Neuroscience.

Dopamine and Motivation

"Our understanding of dopamine has gone through several reiterations," says Treadway. Decades ago, he says, it was known mainly as the ''pleasure chemical."

Experts know, however, that it also plays a role in behavior, voluntary movement, motivation, and reward, among other activities.

In other studies, experts have found that manipulating dopamine has an effect on decisions about working hard for rewards.

Treadway wanted to focus on how the naturally occurring variation in dopamine in people affects their desire to work hard.

With colleagues from Vanderbilt University, he evaluated 25 healthy men and women ages 19 to 29. They spent about 20 minutes in the lab, completing button-pushing tasks.

Some were difficult tasks. Others were easy. For instance, a hard task required pushing a keyboard button 100 times in 21 seconds with a non-dominant pinky finger.

An easy task would be pushing a keyboard button 30 times in seven seconds, using a dominant index finger, Treadway says.

The rewards varied, from about $1 for easy to over $4 for the hard tasks.

Treadway did brain imaging tests known as positron emission tomography, or PET scans. This allowed him to look at levels of dopamine within different brain areas.

Today on WebMD

Differences between feeling depressed or feeling blue.
lunar eclipse
Signs of mania and depression.
man screaming
Causes, symptoms, and therapies.
woman looking into fridge
When food controls you.
Woman standing in grass field barefoot, wind blowi
senior man eating a cake
woman reading medicine warnings
depressed young woman
man with arms on table
man cringing and covering ears

WebMD Special Sections