Skip to content
My WebMD Sign In, Sign Up

Migraines & Headaches Health Center

Font Size

Antiseizure Medicines for Cluster Headaches

Antiseizure medicines are sometimes used to prevent the frequency or recurrence of cluster headaches, which are cycles of painful, one-sided headaches. Antiseizure medicines most often prescribed for cluster headaches include valproate and topiramate. These medicines are usually tried with another medicine to prevent cluster headaches.

It is not clear exactly how antiseizure medicines work to reduce cluster headaches or migraines. Antiseizure medicines are usually taken daily in small doses and then gradually increased until your symptoms subside or the side effects become intolerable.

Recommended Related to Migraines/Headaches

Ocular Migraine Treatment

Since it is brief, the vision loss of ocular migraines is not usually treated. But you may need relief for the headache that accompanies or follows it. The primary treatment for ocular migraines is to reduce exposure to triggers. Calcium-channel blockers are the main drug treatment for ocular migraines. They work by relaxing the blood vessels. One example is Cardene, which can be given as a pill or as a tab you put under the tongue. There is some evidence that nitroglycerin or Diamox may also h...

Read the Ocular Migraine Treatment article > >

Common side effects include:

The U.S. Food and Drug Administration (FDA) has issued a warning on antiseizure medicines and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take antiseizure medicine should be watched closely for warning signs of suicide. People who take antiseizure medicine and who are worried about this side effect should talk to a doctor.

ByHealthwise Staff
Primary Medical ReviewerAnne C. Poinier, MD - Internal Medicine
Specialist Medical ReviewerSeymour Diamond, MD - Neurology
Last RevisedApril 9, 2010

WebMD Medical Reference from Healthwise

Last Updated: April 09, 2010
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

Today on WebMD

Headache Triggers Slideshow
Slideshow
depressed woman with headache
Slideshow
 
Woman with headache making face
Tool
mother holding her head
Article
 
woman receiving acupuncture
Slideshow
Hands reaching for medicine
Article
 
Migraines Headaches Basics
Article
acupuncture needles in woman's back
Slideshow
 
Hormones Headaches
Articles
healthy lifestyle items
Article
 
Sinusitis
Slideshow
headache in the bedroom
Article
 

Special Sections